The House of Medici A summary by Jacob Jason Demedici The House of Medici ( /ˈmɛdɪtʃi/ MED-i-chee ; Italian pronunciation: [ˈmɛːditʃi]) was an Italian banking family and political dynasty that first began to gather prominence under Cosimo de’ Medici in the Republic of Florence during the first half of the 15th century. The family originated